与受体相互作用的蛋白激酶2是胰腺癌的免疫治疗点

Wenhua Sang1, Yiduo Zhou2, Haiyan Chen3

  • 1Department of Colorectal Surgery & Oncology of the Second Affiliated Hospital, and Department of Pathology & Pathophysiology, Zhejiang University School of Medicine, Hangzhou, China.

Cancer discovery
|October 12, 2023
PubMed
概括

在胰腺癌 (PDAC) 中准受体相互作用蛋白激酶2 (RIPK2) 克服了免疫逃避. 抑制RIPK2增强了抗PD-1免疫疗法,在PDAC模型中改善了生存率和瘤回归.

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