血红蛋白和血红蛋白之间的关系:一个系统的审查和元分析
Kevin L Webb1,2, Ellen K Gorman1, Olaf H Morkeberg1
1Department of Anesthesiology and Perioperative Medicine, Mayo Clinic, Rochester, Minnesota, United States of America.
PloS one
|October 12, 2023
概括
最大氧气吸收 (绝对VO2) 与血红蛋白水平有积极的关联. 这种关系在观察性和干预性研究中都是正确的,表明血红蛋白.
科学领域:
- 运动生理学 运动生理学
- 血液学 血液学 血液学
- 运动医学 运动医学
背景情况:
- 血红蛋白对于氧气运输至关重要.
- 血红蛋白和最大氧气摄取量 (VO2max) 之间的关系是复杂的,也是有争议的.
- 现有的文献显示了关于这种关联的相当大的变化.
研究的目的:
- 综合分析现有的关于血红蛋白水平与最大氧气摄取量 (max) 之间的关系的文献.
- 通过观察性和干预性研究设计来检查协会.
- 为了研究血红蛋白度/质量和绝对/相对最大值之间的联系.
主要方法:
- 系统的文献搜索于2021年12月进行,遵循PRISMA指南.
- 数据的提取和选择由两个独立的审稿人进行.
- 对观察性研究进行元回归,对干预性研究进行元分析,以评估与血红蛋白修饰相关的max变化.
主要成果:
- 分析了384项研究 (226项观察研究,158项干预研究).
- 观察数据显示,绝对VO2max和血红蛋白水平 (度,质量,血红素值;P<0.001) 之间存在显著的正相关性.
- 干预数据显示,绝对VO2max变化和血红蛋白水平变化 (度P<0.0001,质量P=0.006) 之间存在显著的正相关性.
结论:
- 最大氧吸收 (VO2max) 与研究类型的血红蛋白水平密切相关.
- 结果表明没有明显的基于性别的差异,尽管对女性的数据有限.
- 需要进一步的研究来详细探索性别特异性反应.
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