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类飞的前腿是新的特征,而不是腿的同类
Yuji Matsuoka1, Suriya Narayanan Murugesan1, Anupama Prakash1
1Department of Biological Sciences, National University of Singapore; 14 Science Drive, Singapore 117543 Singapore.
Science advances
|October 12, 2023
概括
蝶幼虫的前腿不是胸部腿的连续同类. 基因表达分析表明,前肢从一个独特的基因网络中发展,表明它们是新的特征.
科学领域:
- 发育生物学是发展生物学.
- 进化生物学是进化的生物学.
- 昆虫学 昆虫学是一门学科.
背景情况:
- 虫幼虫拥有胸部腿和腹部前腿,但它们的进化关系尚不清楚.
- 了解这些附录之间的同质性对于昆虫进化研究至关重要.
研究的目的:
- 为了调查类鸟的胸部腿和腹部前腿是否是连续同类.
- 为了确定参与prolegs发展的基因调控网络 (GRNs).
主要方法:
- 来自Bicyclus anynana*幼虫的各种附属物的RNA测序.
- 对基因表达模式的分析,包括霍克斯基因和附属体标记基因.
- 研究部分*腹部-A* (abd-A) 淘汰对尾发育的影响.
主要成果:
- 前肢转录组类似于头角转录组,而不是胸部腿转录组.
- 在*abd-A*淘汰中,胸腿同类物和前腿在同一部分发展,反驳了序列同类.
- 脚表达终端标记基因 (*果*, *Distal-less*),但缺乏质标记基因,这表明一个模块化的终端GRN.
- 霍克斯基因*abd-A*在抑制腿部发育和潜在地激活前腿部发育方面发挥着作用.
结论:
- 类飞的前腿不是胸部腿的连续同类.
- 长腿很可能是从腹部中先前存在的模块化末端GRN的激活进化而来的.
- 霍克斯基因*abd-A*与前足的新奇进化有关.
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