藻类开花期间活跃巨型病毒感染的每日营业额由单细胞转录组学揭示
Gur Hevroni1, Flora Vincent1, Chuan Ku1
1Department of Plant and Environmental Sciences, Weizmann Institute of Science, Rehovot, 7610010, Israel.
Science advances
|October 12, 2023
概括
巨型病毒感染海洋藻类,影响海洋的繁荣. 单细胞分析揭示了早期感染阶段和持续的病毒活动,影响了更广泛的微生物社区和宿主生理学.
科学领域:
- 海洋微生物学 海洋微生物学
- 病毒学 病毒学
- 单核细胞生物学 单核细胞生物学
背景情况:
- 巨型病毒显著影响海洋生态系统,特别是像藻类这样的单细胞真核生物.
- 在自然海洋环境中量化活跃病毒感染在方法上具有挑战性.
- 花是海洋碳循环和食物网的关键组成部分.
研究的目的:
- 通过单细胞分辨率,研究天然花花中巨型病毒感染的动态.
- 为了将病毒感染状态与宿主生理特征和开花动态相关联.
- 了解病毒活动对海洋微生物群落的持续影响.
主要方法:
- 单细胞RNA测序 (scRNA-seq) 用于描述病毒和宿主转录组.
- 分析了大约12,000个来自海洋花朵的单独的尾虫细胞.
- 病毒感染水平,开花强度和宿主细胞化之间的相关性分析.
主要成果:
- 病毒感染在开花阶段早期被检测出来,与开花强度相反相关.
- 一定比例的受感染细胞在几天内显示出早期的病毒复制,这表明每天的营业额.
- 受感染的可可利多甚至在感染的后期阶段也保持了化.
- 病毒细胞相关代谢物的持续产生可能会影响周围的微生物群.
结论:
- 单细胞分辨率对于理解自然种群中宿主病毒动态至关重要.
- 巨型病毒感染影响藻类生理学和代谢物生产,影响海洋食物网.
- 这项研究强调了海洋花中病毒感染的持久性和动态性.
相关概念视频
Red Algae
38
Red algae, also known as rhodophytes, are primarily found in marine environments, though some species inhabit freshwater and terrestrial ecosystems. These organisms exist in both unicellular and multicellular forms, with some multicellular varieties reaching macroscopic sizes.As phototrophic organisms, red algae contain chlorophyll a; however, their chloroplasts lack chlorophyll b. Instead, they possess phycobiliproteins, which serve as major light-harvesting pigments, similar to those found in...
38
Viral Recombination
23.5K
Cells are sometimes infected by more than one virus at once. When two viruses disassemble to expose their genomes for replication in the same cell, similar regions of their genomes can pair together and exchange sequences in a process called recombination. Alternatively, viruses with segmented genomes can swap segments in a process called reassortment.
23.5K


