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普遍的G × E相互作用塑造了适应性轨迹,并在人工选择实验中探索了表型空间
Arnaud Desbiez-Piat1,2, Adrienne Ressayre1, Elodie Marchadier1
1Université Paris-Saclay, INRAE, CNRS, AgroParisTech, GQE-Le Moulon, Gif-sur-Yvette 91190, France.
Genetics
|October 12, 2023
概括
长期选择实验显示,既存在的突变,又出现的新突变都能推动进化反应. 通过环境相互作用了解突变效应和基因型对于预测定量遗传学中选择界限至关重要.
科学领域:
- 进化遗传学 进化遗传学
- 量化遗传学 量化遗传学
- 植物育种 植物育种
背景情况:
- 长期选择反应受初始遗传变异和新突变的影响.
- 环境 (G×E) 相互作用对其他特征和基因型的相关选择可以使选择反应分析复杂化.
研究的目的:
- 量化定位和突变变异常对选择反应的贡献.
- 估计基因型突变效应并分析G×E相互作用.
- 调查特征相关性如何影响现型空间探索.
主要方法:
- 在玉米开花时间使用了Saclay分离选择实验 (DSEs).
- 来自年度测量 (DSEYM) 和常见花园实验 (DSECG) 的组合基因型和表型数据.
主要成果:
- 有效突变的验证丰富,平均影响为+0.278至+0.299天.
- 观察到不良突变的固定 (高达25%),可能是由于对抗性类型和G×E相互作用.
- 发现保存的全球特征与时间模式的相关性,以及对弱相关性特征的随机表型探索.
结论:
- 有益的突变通过选择得到丰富,但对抗性类型和G×E相互作用有助于遗传负载.
- 特征相关性影响了表型空间的探索,弱相关性特征显示了随机模式.
- 了解突变动态和G×E相互作用是预测选择限制和优化育种策略的关键.
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