怀孕前健康的生活方式和不良怀孕结果
Siwen Wang1, Makiko Mitsunami, Eduardo Ortiz-Panozo
1Department of Nutrition and the Department of Epidemiology, Harvard T.H. Chan School of Public Health, the Division of Women's Health, the Division of Preventive Medicine, and the Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, and Harvard Medical School, Boston, Massachusetts.
Obstetrics and gynecology
|October 12, 2023
概括
在怀孕前采取健康的生活方式,包括良好的饮食和健康的体重,可显著降低怀孕不良结果的风险. 这种生活方式可以预防近20%的妊娠并发症.
科学领域:
- 生殖健康 生殖健康
- 预防医学 预防医学
- 流行病学 流行病学
背景情况:
- 怀孕不良后果对母亲和婴儿的健康构成重大风险.
- 识别诸如生活方式等可修改因素对于预防策略至关重要.
研究的目的:
- 检查妊娠前健康生活方式因素与不良妊娠结果风险之间的关联.
- 确定采用健康生活方式对预防妊娠并发症的潜在影响.
主要方法:
- 从护士健康研究II (NHSII) 中收集的前性数据的二次分析.
- 包括没有慢性疾病的女性,在怀孕前评估生活方式因素 (BMI,吸烟,体力活动,饮食,酒精,多维生素).
- 妊娠不良事件的综合结果,包括流产,妊娠糖尿病,孕前,早产等.
主要成果:
- 分析了超过15,000名妇女和27,000次怀孕;35.8%的人经历了不良结果.
- 由六个因素定义的健康生活方式显示了与不良妊娠结果的剂量依赖逆相关性 (P趋势<.001).
- 具有所有六个健康因素的女性的不良结果风险降低了37%,特别是妊娠糖尿病,妊娠高血压和低出生体重.
结论:
- 怀孕前健康的生活方式与减少怀孕不良结果的风险密切相关.
- 在怀孕之前实施健康生活方式干预措施可能是预防的有效策略.
- 健康的BMI,饮食质量和多种维生素的使用显示出最强的保护性关联.
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