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Updated: Jul 13, 2025

High-Throughput Cellular Profiling of Targeted Protein Degradation Compounds Using HiBiT CRISPR Cell Lines
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与类似-1的葡萄糖合使得向蛋白质降解成为可能

Liquan Zhu1, Yiyu Zhou1, Bei Zhang1

  • 1Key Laboratory of Bioorganic Synthesis of Zhejiang Province, College of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou 310014, China.

Bioorganic chemistry
|October 12, 2023
PubMed
概括

新的葡萄糖类1受体向化基因 (GLP-1-LYTACs) 能够实现向蛋白质降解. 这种方法有效降解细胞外和细胞膜蛋白质,扩大了 lysosome-targeting 嵌合体的实用性.

关键词:
欧洲农业基金会 (EGFR) 是一个.这就是GLP-1.在LYTAC中,我们可以使用LYTAC在PD-L1中.蛋白质降解 蛋白质降解

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