[怀孕期间初级甲状腺功能障碍症的诊断和治疗:系统性审查和纵向病例研究]
Inesse Ait Amara1, Diana Bula-Ibula1
1CHU de Brugmann, place A.-Van-Gehuchten 4, 1020 Bruxelles, Belgique.
Gynecologie, obstetrique, fertilite & senologie
|October 12, 2023
概括
怀孕期间的原发性甲状腺功能增强症对母亲和胎儿都有风险,手术是唯一的治疗方法. 早期诊断和治疗,理想情况下是第二个三个月的手术,对于更好的结果至关重要.
科学领域:
- 内分泌学 在内分泌学.
- 产科和妇科 产科和妇科
背景情况:
- 初级甲状腺功能障碍症 (PHP) 是甲状腺类激素的过度产生导致高血症.
- 怀孕期间的诊断是具有挑战性的,因为重叠的症状和生理缺血症.
- 甲状腺腺瘤是最常见的原因,通常通过超声波检测.
研究的目的:
- 为了澄清妊娠期间初级甲状腺功能障碍的发展,并发症,危险因素和治疗.
- 在没有针对孕妇的具体管理建议的情况下,提供指导.
主要方法:
- 用PubMed,Cochrane图书馆和Science Direct数据库进行的文献评论.
主要成果:
- 怀孕期间的PHP存在诊断挑战,并对孕妇和胎儿造成重大风险.
- 孕产妇的并发症范围在14-67%,其中高血危机是最严重的.
- 胎儿并发症发生在45-80%的病例中,主要是新生儿低血症;还注意到诸如多水症和生长迟缓等产科问题.
结论:
- 手术干预是孕期PHP的最终治疗方法.
- 对于有症状的患者或水平升高的患者,应考虑进行手术.
- 手术的最佳时间是怀孕的第二个三个月,经过跨学科的讨论,以尽量减少孕产妇和胎儿的风险.
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