perfluorooctanoic 酸通过甲状腺细胞中的 TSH-TSHR 信号通路破坏甲状腺特异性基因表达和调节

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Updated: Jul 13, 2025

Author Spotlight: In Vivo Assessment of Thyroid Hormone Disruption Using the THAI Mouse Model
04:14

Author Spotlight: In Vivo Assessment of Thyroid Hormone Disruption Using the THAI Mouse Model

Published on: October 6, 2023

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Yatao Du1, Chaojie Chen2, Guangdi Zhou1

  • 1Ministry of Education-Shanghai Key Laboratory of Children's Environmental Health, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200292, China.

Environmental research
|October 12, 2023
PubMed
概括

perfluorooctanoic 酸 (PFOA) 通过干扰TSH激活的cAMP通路来破坏甲状腺功能,影响关键基因和TSHR调节. 这种机制可能有助于降低甲状腺素水平,提供潜在的干预目标.

关键词:
压力ERER压力ERER压力葡萄糖基酶化是什么? 葡萄糖基酶化是什么甲状腺功能低下症 甲状腺功能低下症perfluorooctanoic 酸 的含量是多少这是一个TSH受体.

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