在癌症治疗中输送的超分子纳米结构
Priyanka Das1, Manasa N1, Nidhi Singh1
1Polymer-Based Medical Devices and Complex Drug Delivery Systems Laboratory, Department of Pharmaceutics, National Institute of Pharmaceutical Education and Research (NIPER), Kolkata, India.
The Journal of pharmacology and experimental therapeutics
|October 12, 2023
概括
超分子纳米结构 (SN) 通过控制药物释放和向特定细胞来提供先进的癌症治疗. 基于的SN显示了个性化癌症治疗的巨大前景,改善了患者的治疗结果.
科学领域:
- 生物医学工程 生物医学工程
- 纳米技术纳米技术
- 在瘤学瘤学.
背景情况:
- 超分子纳米结构 (SN) 正在成为癌症治疗的关键药物递送系统.
- 这些系统提供可控释放和增强的治疗疗效.
- 因其生物相容性和瘤特异性向在癌症治疗中得到越来越多的认可.
研究的目的:
- 审查用于药物输送的SN的基本原理.
- 探索使用SN的各种药物递送机制.
- 介绍基于的SNs在癌症治疗中的最新进展.
主要方法:
- 关于超分子纳米结构的当前文献的综述.
- 自组装结构的分析,包括小分子,聚合物,和蛋白质.
- 基于的自组装纳米系统及其可调节性质的检查.
主要成果:
- SNs提高了药物的溶解性,稳定性和向性输送.
- 基于的SN显示可调整的形态和对瘤细胞的高特异性.
- 这些纳米结构具有个性化癌症医学的巨大潜力.
结论:
- SNs代表了癌症药物输送的一个有前途的平台.
- 基于的SNs为向癌症治疗提供了灵活和有效的方法.
- 对SNs的进一步研究可以改善瘤学患者的治疗结果.
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