在维护血液透析患者的认知障碍的预测模型
Ding Chen1, Chang Xiao1, Wangyan Xiao1
1Department of Nephrology, Air Force Medical Center, PLA, No.30, Fucheng Road, Haidian District, Beijing, 100037, China.
BMC neurology
|October 12, 2023
概括
这项研究确定了在接受维持血液透析 (MHD) 的患者中认知障碍的关键风险因素. 开发了一个预测模型来评估这些患者的认知衰退风险.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學.
- 神经学 神经学
- 老年病的医生 老年病的医生
背景情况:
- 认知障碍是末期病 (ESRD) 患者接受维持血液透析 (MHD) 的重要问题.
- 识别风险因素和开发预测工具对于早期干预和对这一群体认知能力下降的管理至关重要.
研究的目的:
- 调查MHD患者认知障碍相关的风险因素.
- 开发和验证ESRD患者MHD认知障碍的预测模型.
主要方法:
- 146名患有ESRD的MHD患者使用蒙特利尔认知评估 (MoCA) 进行了评估.
- 多变量后勤回归确定了风险因素,并使用接收器运行特征曲线来构建预测模型.
- 一个多因素预测模型根据证据的权重将风险分类.
主要成果:
- 认知障碍的患病率为31.5% (146名患者中有46名).
- 重要风险因素包括年龄较大 (≥55岁),透析时间较长 (≥5年) 和目前的吸烟.
- 开发的预测模型显示认知障碍的高预测值为84%.
结论:
- 针对MHD患者的认知障碍,成功构建了一个多因素预测模型.
- 该模型具有很高的预测价值,有助于识别有风险的个人.
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