微生物组对宿主的进化后果:对宿主健康,特征和遗传能力的影响
Anna M O'Brien1,2, Jason R Laurich2, Megan E Frederickson2
1Department of Molecular, Cellular, and Biomedical Sciences, University of New Hampshire, Durham, NH, United States.
Evolution; international journal of organic evolution
|October 13, 2023
概括
主体基因型显著影响草的健康状况和特征,微生物群相互作用进一步影响这些影响. 观察到宿主及其微生物群之间的局部适应,影响了适应性和特征遗传性.
科学领域:
- 生态生态学 生态生态学
- 进化生物学 进化生物学
- 微生物组研究 微生物组研究
背景情况:
- 生物体的表型和健康是由宿主基因组 (G),微生物组 (G) 和环境 (E) 之间的复杂相互作用形成的.
- 这些基因型对基因型 (G×G),基因型对环境 (G×E) 和G×G×E相互作用对于宿主微生物群共同进化至关重要,但很少同时研究.
- 了解这些多因素相互作用是预测生物适应和生态成功的关键.
研究的目的:
- 研究宿主基因型,微生物组和环境对Lemna minor (草) 的健康状况和特征的相互作用影响.
- 在单个实验框架中比较G×G,G×E和G×G×E相互作用的相对贡献.
- 探索草及其相关微生物群之间的局部适应证据.
主要方法:
- 从城市到农村梯度的10个地点收集和培养Lemna minor及其相关微生物组.
- 在两个环境 (低和高) 中,实体操纵宿主基因型 (10个基因型) 和微生物群 (10个微生物群).
- 在200种实验性治疗中分析了宿主健康和特征,微生物组合和特征遗传性的变化.
主要成果:
- 宿主基因型解释了子的健康状况和特征中最大比例的变化.
- 微生物组对宿主特征的影响显著依赖宿主基因型 (G×G相互作用).
- 当引入的微生物组与宿主本地微生物组相匹配时,宿主健康和微生物生长增加,这表明本地适应.
结论:
- 微生物组组成显著影响宿主健康状况,特征表达和特征的遗传性.
- G×G相互作用在调解宿主微生物组关系方面发挥着至关重要的作用.
- 这些发现对理解宿主微生物群的共同进化和基于微生物群的育种策略有重大影响.
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