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Updated: Jul 13, 2025

Capillary Electrophoresis Separation of Monoclonal Antibody Isoforms Using a Neutral Capillary
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一种新的方法,通过结合移位模式染色学和阶段化分离,对单克隆抗体电荷变异进行连续染色学分离

Anupa Anupa1, Vikrant Bansode2, Nikhil Kateja2

  • 1School of Interdisciplinary Research, Indian Institute of Technology Delhi, New Delhi, India.

Biotechnology progress
|October 13, 2023
PubMed
概括

这项研究引入了一种新的连续阴离子交换染色学 (CEX) 方法,使用位移模式和阶段化来分离单克隆抗体电荷变异. 这种方法在连续生物制造中提高了工艺效率和产品质量控制.

关键词:
生物类似药的生物类似药.阴离子交换色谱学 阴离子交换色谱学收费变种 收费变种连续加工是连续的加工.一个单克隆抗体.样品的移位情况.

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