韩国卫生检查中的睡眠时间,并发症和死亡率:一项前性队列研究
Sukhong Min1, Woo-Kyoung Shin1,2, Katherine De la Torre1,3
1Department of Preventive Medicine, Seoul National University College of Medicine, Seoul, Korea.
长时间睡眠 (≥8小时) 与韩国成年人全因死亡率的增加有关,即使考虑到健康状况. 需要进一步的研究来理解这种睡眠死亡率的关联.
科学领域:
- 流行病学 流行病学
- 睡眠医学 睡眠医学
- 公共卫生 公共卫生
背景情况:
- 睡眠时间延长与死亡率之间的联系经常受到争议,原因是潜在的混因素,如并发症.
- 之前调整并发症的研究对这种关联产生了相互矛盾的结果.
研究的目的:
- 为了研究长时间睡眠时间和死亡率之间的关联,在一个大规模的韩国前队列中.
- 评估伴随性疾病是否影响睡眠时间和死亡率之间的关系.
主要方法:
- 来自健康检查者研究的114,205名参与者的队列被跟踪了中位数9.1年.
- 为21种疾病创建了一个复合并发性得分.
- 考克斯比例危险回归被用来估计死亡风险,调整各种因素和并发症得分. 进行了分层分析.
主要成果:
- 经过调整后,发现睡眠8小时或更长时间与全因死亡率 (HR,1.10;95% CI,1.01至1.20) 之间存在关联.
- 在基于并发症状态的分层分析中,这种关联并不显著.
结论:
- 长时间的睡眠时间与韩国人口的全因死亡率有关,独立于相关疾病.
- 需要进一步研究睡眠时间与死亡率相关的机制.
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