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在ex vivo组织切片中通过TAT-Cre复合酶媒介的化基基基基基基基基改造的一种方法

Sek-Shir Cheong1, Tiago C Luis2, Michelle Stewart3

  • 1National Heart and Lung Institute (NHLI), Imperial College London, London SW7 2AZ, UK.

Disease models & mechanisms
|October 13, 2023
PubMed
概括

研究人员开发了一种新方法,即TAT-Cre复合酶介导的组织切片 (TReATS) 中的浮性等位基因修饰,用于精确切割肺切片 (PCLS) 中的精确基因操纵. 这种技术使得在ex vivo肺组织模型中能够快速删除或激活基因.

关键词:
基因基因基因的修改细胞透的CRE复合酶可以重组.基因操纵 基因操纵是什么精密切割的肺部切片.精确切割的组织切片.这就是TAT-Cre.

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