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Updated: Jul 13, 2025

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遗传密码扩展和光敏感UAA在研究膜蛋白中的应用

Shu Zhao1, Dong Liu1

  • 1School of Life Sciences, Nantong Laboratory of Development and Diseases, Nantong University, Nantong, 226019, China.

Open life sciences
|October 13, 2023
PubMed
概括

本综述强调了光敏感非自然氨基酸 (UAA) 和遗传密码扩展 (GCE) 如何使光控制的研究能够研究膜蛋白的功能,为生物研究提供了新的策略.

关键词:
遗传密码扩展 扩展 遗传密码离子通道 离子通道照明控制器 照明控制器膜受体是一种膜受体.具有光敏感性的UAA.

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Proteins show rotational as well as lateral diffusion across the membrane. The lateral diffusion of proteins was confirmed through the cell fusion experiment where mouse and human cells were fused, resulting in hybrid cells. When the human and mouse cells fused, the specific membrane proteins on human and mouse cells were marked with the red and green-fluorescent markers, respectively. Initially, the red and green fluorescence was located on the respective hemisphere of the cell. As time...
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