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Updated: Jul 13, 2025

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通过转录基因分析揭示了T细胞中低甲基化诱导的调节程序

Memnon Lysandrou1, Panagiota Stamou1, Dionysia Kefala1

  • 1Bone Marrow Transplantation Unit and Institute of Cell Therapy, University of Patras, Rio, Greece.

Frontiers in immunology
|October 13, 2023
PubMed
概括

低甲基化剂将T细胞转化为强大的诱导调节性T细胞 (iTregs),表达HLA-G. 这些通过RNA-seq分离的HLA-G阳性 (G+) 细胞显示出独特的免疫抑制机制,与FOXP3.3不同.

关键词:
在 HLA-G 的情况下.在 IDO-1 中使用.在RNA-Seqq.这就是ScRNA-seqq.低甲化剂是一种低甲化剂.监管性的T细胞.

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