在儿童中可能的里瓦罗克萨班诱导的多形红:一个病例报告
Zhongqiang Cao1,2, Zhengran Fu1, Ying Liu1
1Department of Pharmacy, Beijing Children's Hospital, Capital Medical University, Beijing 100045, China.
概括
里瓦罗克萨班是适用于儿童的药物,可能会导致多形红斑. 一个5.5岁的女孩在服用抗脂综合征的里瓦罗克萨班后出现了这种皮疹,这种皮疹在改变药物后消失了.
科学领域:
- 儿科药理学 儿科药理学
- 皮肤病学 皮肤病学
- 血液学 血液学 血液学
背景情况:
- 有限的数据存在于rivaroxaban在儿科患者的使用.
- 在儿童中抗脂综合征 (APS) 管理.
- 在儿科患者群体中调查药物不良反应.
研究的目的:
- 报告一名儿科患者可能患有里瓦洛克萨班诱导的多样性红疹病例.
- 为了解利瓦洛克萨班在儿童中的安全概况做出贡献.
- 描述这种不良事件的临床表现和管理.
主要方法:
- 一个55岁的女性患有APS的病例报告.
- 口服里瓦罗克萨班2.5毫克每天两次,持续16天.
- 皮肤表现和治疗反应的临床观察.
主要成果:
- 患者出现了,随后出现了泛性多种红斑.
- 停止服用里瓦罗克萨班并开始替代治疗导致了改善.
- 转换为华法林和纳德罗巴林导致红血的减少.
结论:
- 里瓦罗克萨班可能与儿科患者的多形红斑有关.
- 及时识别和管理对于药物不良反应至关重要.
- 需要进一步的研究来确定因果关系和发病率.
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