在第二次Covid-19疫苗接种5个月后,对Covid-19抗尖峰IgG抗体的评估
Reyhaneh Alipoor Rafie1,2, Leila Azimi2, Shahnaz Armin2
1Department of Infectious Diseases, Shahid Beheshti University of Medical sciences, Tehran, Iran.
GMS hygiene and infection control
|October 13, 2023
概括
在接种第二剂COVID-19疫苗5个月后,医疗保健工作者表现出高IgG抗抗体标位. 职业领域和之前的COVID-19感染影响了抗体水平,这表明大多数接种疫苗的员工具有持续的免疫力.
科学领域:
- 免疫学 免疫学 免疫学
- 疫苗学 疫苗学 疫苗学
- 公共卫生 公共卫生
背景情况:
- 在COVID-19疫苗接种后,抗体标位显著变化.
- 评估长期免疫反应对于评估疫苗疗效至关重要.
研究的目的:
- 在第二次COVID-19疫苗接种5个月后,在医疗保健工作者中确定IgG抗尖峰抗体标位.
- 评估影响抗体水平的因素,包括疫苗类型和职业暴露.
主要方法:
- 使用ELISA对IgG抗SARS-CoV-2尖端蛋白抗体标位的血清学评估.
- 研究人群:医疗保健人员在接种第二剂疫苗 (斯普特尼克V,西诺药,阿斯特拉泽内卡) 后五个月.
主要成果:
- 观察到高患病率的阳性抗峰IgG抗体 (96.4%).
- 平均IgG标位为4.3±2.29单位.
- 抗体标位与职业领域和COVID-19病史有显著联系.
结论:
- 大多数接种疫苗的医疗保健工作者在接种第二剂疫苗后5个月内保持高IgG抗抗体标位.
- 职业因素在调节对COVID-19疫苗接种免疫反应方面发挥着作用.
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