快速增长的子宫肌瘤 - 我们应该害怕它吗?
Marek Nowak1,2, Wojciech Bartosik1, Weronika Witana1
1Department of Operative Gynecology and Gynecologic Oncology of Polish Mother's Memorial Hospital - Research Institute, Łódź, Poland.
Przeglad menopauzalny = Menopause review
|October 13, 2023
概括
子宫纤维瘤,或肌肉瘤,可以从年到年大大改变大小. 虽然通常是良性的,但快速生长需要对潜在症状或罕见恶性瘤进行调查.
科学领域:
- 妇科 妇科 妇科 妇科
- 在瘤学瘤学.
- 生殖医学 生殖医学
背景情况:
- 子宫肌瘤 (纤维瘤) 呈现出可变的生长模式,在绝经前妇女中,年增长率为20-30%.
- 自发回归发生在约20%的女性中,肌肉瘤通常在绝经后稳定或回归.
- 绝经后出现的新的或扩大的子宫病变需要进行彻底的诊断.
研究的目的:
- 审查快速生长的子宫肌瘤的临床影响和诊断考虑.
- 为了澄清子宫纤维瘤生长率与乳腺肌肉瘤风险之间的关联.
- 根据患者的因素和瘤特征,概述子宫纤维瘤的个性化治疗策略.
主要方法:
- 文献综述和对有关子宫纤维瘤生长动态的现有数据的分析.
- 检查与症状和无症状快速生长肌肉瘤相关的临床结果.
- 在子宫纤维瘤 (包括快速生长的子宫纤维瘤) 中评估雷奥美索尔科马的患病率和危险因素.
主要成果:
- 快速生长的子宫纤维瘤可能会导致症状,不育,并引起人们对恶性瘤的担忧,尽管肉瘤的风险很低 (总体上为0.26%,快速生长的肌肉瘤为0.27%).
- 肉瘤风险与子宫大小或肌肉瘤扩大的速度无关.
- 治疗子宫肌瘤的决定,包括快速生长的子宫肌瘤,应该是个性化的,考虑患者的年龄,生育欲望,症状和瘤特征.
结论:
- 快速生长的子宫肌瘤需要仔细评估,特别是绝经后,以排除恶性瘤和控制症状.
- 乳腺髓肉瘤的风险始终很低,无论肌肉瘤的生长速度或大小如何.
- 对于子宫纤维瘤,最好采用最少的侵入性手术方法,并以肉瘤风险评估为指导治疗决策.
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