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Updated: Jul 13, 2025

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四级化合物的食物和胆汁微粒结合

Takeru Sumiji1, Kiyohiko Sugano1

  • 1Molecular Pharmaceutics Lab., College of Pharmaceutical Sciences, Ritsumeikan University, 1-1-1, Noji-higashi, Kusatsu, Shiga 525-8577, Japan.

ADMET & DMPK
|October 13, 2023
PubMed
概括

食物摄入量显著降低了四级化合物 (QACs) 的口服吸收,因为它们与胆汁和食物成分结合. 这项研究研究了QAC药物的这种负面食物效应机制.

关键词:
动态透析是一种动态透析.通过肠膜的透.对食物产生负面影响模拟了肠道液体的模拟.没有绑定的分数.

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