表面扩散系数值在诊断急性脊髓缺血时的有用性
Norikazu Koori1,2, Joe Senda3, Takehiro Naito4
1School of Health Sciences, Ibaraki Prefectural University of Health Sciences, Inashiki, Japan.
Nagoya journal of medical science
|October 13, 2023
概括
表面扩散系数 (ADC) 值可以帮助诊断急性脊髓缺血. 脊髓缺血患者的较低ADC值表明这种情况,有助于早期检测.
科学领域:
- 放射学 放射学是一门学科.
- 神经学 神经学
- 医疗成像医学成像
背景情况:
- 脊髓缺血是一种急性病症,需要及时诊断.
- 从正常的脊髓区分急性脊髓缺血可能是一个挑战.
研究的目的:
- 评估表面扩散系数 (ADC) 值在区分正常脊髓与急性缺血脊髓的有用性.
- 确定ADC测量是否可以作为急性脊髓缺血的诊断生物标志物.
主要方法:
- 使用扩散权重成像测量了113名对照组和8名急性脊髓缺血患者的ADC值.
- 在症状出现后的初始成像时记录了ADC值.
主要成果:
- 与对照组相比,急性脊髓缺血患者的平均ADC值显著较低 (0.70 ± 0.15 × 10-3 mm2/s) (0.99 ± 0.19 × 10-3 mm2/s) (P < 0.01).与对照组相比,急性脊髓缺血患者的平均ADC值显著较低 (0.70 ± 0.15 × 10-3 mm2/s).
- 截止点ADC值为0.86 × 10-3mm2/s,表明了高诊断性能 (灵敏度为100.0%,特异性为71.7%,AUC为0.92).
结论:
- 表面扩散系数 (ADC) 值显示出作为诊断急性脊髓缺血的非侵入性工具的希望.
- 测量ADC可以帮助早期和准确识别脊髓缺血.
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