在SARS-CoV-2感染后膀泌尿层中的纤维素微血栓:病例报告
Ly Hoang Roberts1, Bernadette M M Zwaans1,2, Kausar Jabbar3
1Department of Urology, Corewell Health, Royal Oak, MI, USA.
Urology case reports
|October 13, 2023
概括
一名男性患者的持续性尿路症状和盆腔疼痛与之前的SARS-CoV-2感染有关. 用膀水分阻塞和盆地治疗治疗提供了缓解,但随着再感染,症状复发,这表明炎症的作用.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 传染性疾病 传染性疾病
- 病理学 病理学 病理学
背景情况:
- 后SARS-CoV-2综合征可以表现为各种尿道和疼痛症状.
- 微血管血栓和炎症可能导致病毒感染后的持续症状.
研究的目的:
- 报告在SARS-CoV-2感染后出现慢性泌尿症状和盆腔疼痛的情况.
- 在这种情况下,调查潜在的病理机制和治疗反应.
主要方法:
- 一名45岁男性的临床病例呈现,他患有先前存在的疾病和SARS-CoV-2后症状.
- 膀活检以评估组织病理,包括微血管变化.
- 用膀水分阻塞和骨盆底物理治疗进行治疗.
- 尿液分析评估炎症标志物,如介质蛋白-8.
主要成果:
- 患者经历了持续的尿动频率,急迫性,夜尿,勃起功能障碍和盆腔/周围骨疼痛.
- 膀活检显示出与出血和纤维素微血栓有关的尿路细胞变化.
- 在膀水分阻塞和盆地治疗后观察到症状改善.
- 在SARS-CoV-2再感染后出现症状的复发和尿路中白蛋白-8水平升高.
结论:
- SARS-CoV-2 感染可能引发慢性泌尿功能障碍和疼痛,可能由微血管炎症介导.
- 膀水分阻塞和盆地治疗可以提供症状缓解.
- 尿路中介素-8的升高表明膀内的局部炎症反应.
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