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Updated: Jul 13, 2025

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Published on: July 30, 2017

在COVID-19后的低血中出现前额功能障碍:EEG/fNIRS研究

Livio Clemente¹, Marianna La Rocca^2,3, Nicola Quaranta¹

¹Department of Translational Biomedicine and Neuroscience (DiBraiN), University of Bari Aldo Moro, Bari, Italy.

Frontiers in human neuroscience

|October 13, 2023

概括

长期患有持续嗅觉丧失的COVID-19幸存者表现出微妙的前额叶皮层缺陷. 这些认知障碍,包括注意力和执行功能减少,可能会影响长期的幸福感.

科学领域:

神经科学是一个神经科学.
传染性疾病传染性疾病
认知科学认知科学

背景情况:

长期COVID-19综合征经常导致认知功能障碍和精神疲劳.
持续性低 (嗅觉减弱) 是长期COVID-19患者的常见症状.
了解这些缺陷的神经生理基础对于有效管理至关重要.

研究的目的:

在有SARS-CoV-2感染史和持续性低的个体中关联认知,神经生理和嗅觉功能.
在COVID-19后的患者中,使用脑电图 (EEG) 和功能近红外光谱学 (fNIRS) 调查前额皮层功能.
用标准化测试来评估认知表现.

主要方法:

在P300奇球和Stroop任务中使用的集成EEG-fNIRS系统.
使用Sniffin' Sticks测试评估的嗅觉功能.
用蒙特利尔认知评估 (MoCA) 和正面评估电池 (FAB) 评估认知功能.

主要成果:

在Stroop任务中,COVID-19后的患者在前额叶皮质中表现出较低的氧血球度.
在COVID-19后的组中观察到P3a响应幅度的减少.
患者在MoCA,Sniffin's Sticks测试和Stroop任务响应延迟方面表现明显差.

结论:

患有持续性低血的COVID-19后患者在感染后4个月内表现出轻微的前额功能缺陷.
这些微妙的缺陷可能会对生活质量和认知健康产生长期影响.
在长期COVID-19中持续监测认知障碍是必不可少的.

关键词:

厌食症是一种厌食症.认知功能障碍认知功能障碍与事件相关的潜力与事件相关的潜力长时间的COVID-19 接近红外光谱学近红外光谱学.

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