出生在布拉德福德的更好的开始 (BiBBS) 干预分娩队列研究:临时队列资料
Josie Dickerson1, Sally Bridges1, Kathryn Willan1
1Born in Bradford, Bradford Teaching Hospitals National Health Service Foundation Trust, Bradford, BD9 6RJ, UK.
Wellcome open research
|October 13, 2023
概括
布拉德福德出生的更好的开始 (BiBBS) 研究成功招募了多样化的家庭,证明了评估早期生活计划的干预队列的可行性. 干预措施的高采用率显示了这一创新研究方法的前景.
科学领域:
- 公共卫生 公共卫生
- 流行病学 流行病学
- 产周研究 产周研究
背景情况:
- 布拉德福德出生的更好的开始 (BiBBS) 干预性分娩队列研究是为了有效评估早期生活干预措施而建立的.
- 干预队列的国际实施正在增加,需要共享可行性和价值数据.
- 本文介绍了BiBBS研究的临时分析,以分享其方法论方法的学习成果.
研究的目的:
- 评估用于早期生命干预的干预性出生队列平台的可行性和价值.
- 报告BiBBS研究中的招聘,样本特征和干预参与情况.
- 提供关于创新的干预队列方法的临时发现.
主要方法:
- 招募BiBBS队列于2016年1月开始,目标是5,000例怀孕,并对2016年1月至2019年11月的数据进行了临时分析.
- 临时分析包括预期产期在2016年4月1日至2020年3月8日之间的怀孕.
- 用描述性统计数据来分析收集的数据.
主要成果:
- 在4823名符合条件的怀孕中,招募了2626名 (54%),包括2392名母亲和2501名儿童.
- 该BiBBS样本代表了怀孕人口,其中巴基斯坦遗产 (61%),白人英国人 (12%) 和其他种族群体的代表性很大.
- 很高比例的参与者 (84%) 居住在贫困地区,85%参与至少一个Better Start Bradford干预,参与度因干预特征而异.
结论:
- BiBBS研究表明,招募一个干预队列的可行性,成功地包括少数民族和贫困背景的罕见听到的家庭.
- 使用这种队列方法,高水平的干预采用令人鼓舞,用于评估多个早期生命干预的过程和结果.
- 包括COVID-19大流行之前,期间和之后的数据,为BiBBS队列增加了显著的科学价值.
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