非洲人高血压风险评估评分和千平方自动交互检测算法:来自SIREN研究的模型
Osahon J Asowata1, Akinkunmi Paul Okekunle1,2, Onoja M Akpa1
1University of Ibadan, Nigeria (O.J.A., A.P.O., O.M.A, A.G.F., J.O.A., O.S.A, G.I.O., O.S.O., R.O.A., M.O.O.).
Hypertension (Dallas, Tex. : 1979)
|October 13, 2023
概括
一个新的风险评分模型准确地识别了非洲人的高血压. 该工具有助于在弱势社区早期发现和预防高血压.
科学领域:
- 心血管健康 心血管健康
- 流行病学 流行病学
- 生物统计学 生物统计学
背景情况:
- 高血压是一个重要的公共卫生问题,特别是在非洲人口中.
- 开发用于早期高血压检测的有效工具对于初级预防策略至关重要.
研究的目的:
- 开发和验证非洲成年人高血压的新型风险评分模型.
- 在研究人群中确定与高血压相关的关键风险因素.
主要方法:
- 使用4413个没有中风的对照组,开发了一种后勤回归模型.
- 数据集分为培训 (80%) 和测试 (20%) 集.
- 风险因素被加权,以创建一个概率风险得分 (0-1);模型准确性被评估使用接收机操作特征 (ROC) 分析和决策树预测.
主要成果:
- 与高血压显著相关的八个因素包括糖尿病,年龄≥65岁,高腰围,BMI≥30 kg/m2,缺乏正规教育,城市居住,家族心血管疾病病史和脂质失调.
- 采用了≥0.60的概率风险得分.
- 该模型表现良好,在测试数据集中ROC为64%;决策树分析显示预测精度为67.7% (培训) 和64.6% (测试).
结论:
- 开发的风险评分模型准确地歧视患有高血压的个体.
- 这种工具可以促进早期识别有风险的非洲个人,以预防初级高血压.
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