[周围水和淋巴系统功能障碍:基于扩散张力磁共振成像的定量评估]
A M Turkin1, T V Melnikova-Pitskhelauri1, L M Fadeeva1
1Burdenko Neurosurgical Center, Moscow, Russia.
Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko
|October 13, 2023
概括
扩散张力MRI (DT-MRI) 揭示了周周血管空间 (ALPS) 索引沿线分析在周周脑的患者中减少,这表明淋巴系统功能障碍在其发病过程中起作用.
科学领域:
- 神经成像是一种神经成像.
- 大脑血管研究研究
- 在瘤学瘤学.
背景情况:
- 周周脑的发病原因尚未完全理解,可能涉及淋巴系统功能障碍.
- 扩散张力MRI (DT-MRI) 和沿周血管空间分析 (ALPS) 指数提供了一种潜在的方法,通过可视化周血管空间的液体流动来评估胀.
研究的目的:
- 在患有 supratentorial 瘤的患者和使用 DT-MRI 的健康志愿者中评估淋巴系统功能.
主要方法:
- 进行了DT-MRI,对52名带有 supratentorial 瘤的患者和6名健康志愿者进行了测试.
- 计算ALPS指数是为了评估沿周血管空间的流体流动.
- 统计分析比较了患者组和对照组之间的ALPS指数.
主要成果:
- 与对照组相比,患有周围焦点的患者在受影响半球中表现出明显较低的ALPS指数.
- 反侧半球的ALPS指数在各组之间是相似的.
- 在对照组中,左半球和右半球之间没有观察到ALPS指数的显著差异.
结论:
- 患有周围焦点的患者受影响半球的ALPS指数降低表明淋巴系统功能障碍.
- 这些发现表明,淋巴系统损伤在周围瘤脑胀的发展中可能发挥作用.
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