肝硬化患者肝脏脑病的ICD-10代码K76.82的诊断性能
Nazli Begum Ozturk1, Laith H Jamil2,3, Elliot B Tapper4
1Department of Internal Medicine, Corewell Health William Beaumont University Hospital, Royal Oak, Michigan, USA.
The American journal of gastroenterology
|October 13, 2023
概括
新的疾病国际分类-10代码K76.82肝脑病变 (HE) 显示出具有高特异性的承诺. 然而,乳糖或利法西明的组合更好地识别HE患者,显示出更高的诊断准确性.
科学领域:
- 肝病学 肝病学是一种肝病学.
- 医疗信息学 医疗信息学
- 诊断的准确性 诊断的准确性
背景情况:
- 肝脏脑病变 (HE) 是肝硬化患者常见的并发症,显著增加了发病率和死亡率.
- 针对HE的特定国际疾病分类-10代码 (K76.82) 于2022年10月1日实施.
研究的目的:
- 为了评估新的HE代码的诊断准确性,K76.82.
- 为了比较K76.82与乳糖和利法西明等已知治疗方法的性能,用于HE诊断.
主要方法:
- 在两个大型卫生系统中评估了K76.82的诊断性能.
- 评估的指标包括灵敏度,特异性,正预测比率和负预测比率.
- 对比K76.82与乳糖,利法西明和ICD-10代码K72.90.
主要成果:
- 总共分析了2,483名患者.
- "乳酪糖或利法西明"的组合达到超过98%的灵敏度.
- 在所有患者队列中,K76.82代码的特异性超过87%.
结论:
- 虽然K76.82代码对识别肝脏脑病的特异性很好,但它比基于治疗的指标敏感度要低.
- 在这项研究中",乳糖或利法西明"的组合被证明是HE的更准确的诊断标记.
- 进一步的研究可能会完善K76.82在临床实践和卫生系统分析中的实用性.
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