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目前的营养和药理方法减轻萨科佩尼亚

Kunihiro Sakuma¹, Kento Hamada¹, Akihiko Yamaguchi²

¹Institute for Liberal Arts, Environment and Society, Tokyo Institute of Technology, Meguro-ku, Tokyo 152-8550, Japan.

|October 13, 2023

概括

预防肉类症包括将抵抗训练与氨基酸补充剂相结合. 虽然一些单独的补充剂表现出有限的效果,但运动与特定的营养物质相结合,显示出对管理与年龄相关的肌肉损失的承诺.

科学领域:

老年学是一门学科.
肌肉生理学肌肉生理学
营养科学营养科学

背景情况:

标志着肌肉质量和力量下降的萨科佩尼亚,增加了老年人群的跌倒风险和软弱.
营养和药理干预对于管理类病至关重要,有限的人类数据需要依赖哺乳动物研究.

研究的目的:

审查对控制肉症的营养和药理学策略的最新研究.
评估各种补充剂和治疗与年龄相关的肌肉损失的疗效.

主要方法:

文献综述侧重于营养和药理学方法对萨科佩尼亚.
包括来自哺乳动物研究的数据,因为人类营养研究的局限性.

主要成果:

将抵抗训练与氨基酸补充剂相结合,是预防肉症的既定方法.
单独使用β-基β-甲基丁酸盐 (HMB) 是无效的,但与运动 (如全身振动) 结合,它可能是有益的.
茶叶甲基因,大豆异黄和乌尔索酸需要进一步的研究;维生素D在没有缺陷的老年人中是无效的;肌静素抑制剂显示出潜在的潜力,但需要谨慎乐观.

结论:

抵抗训练加上氨基酸仍然是预防萨科佩尼亚的黄金标准.
特定的补充剂和新型药理学剂显示出希望,但需要更多的人类临床验证.
目前的证据表明,为了有效地管理皮症,需要采用多方面的方法,结合运动和有针对性的营养或药理干预措施.

关键词:

这就是HMB HMB.卡捷辛是一种可怕的药物.肌肉缩肌肉缩肌肉缩这是我的statin.这种类型的麻症是sarcopenia.乌尔索酸是什么意思乌尔索酸是什么意思维生素D是维生素D的重要组成部分.

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