儿科大病房的处方模式及其与处方错误的关联:一项回顾性观察研究
Aylin N Satir1, Miriam Pfiffner2, Christoph R Meier3
1Department of Hospital Pharmacy, University Children's Hospital Zurich, Zurich, Switzerland. a.satir@unibas.ch.
Drugs - real world outcomes
|October 13, 2023
概括
这项研究分析了儿科住院患者的药物处方模式,发现女性患者和2至11岁的儿童有更高的潜在有害处方错误率. 需要对这些儿科药物安全风险进行进一步的调查.
科学领域:
- 儿科药理学 儿科药理学
- 药物使用研究研究药物使用研究.
- 儿童药物安全性 在儿童中药物安全性
背景情况:
- 有限的数据存在于一般病房的儿科住院患者的药物使用.
- 了解处方模式对于改善儿童药物安全至关重要.
研究的目的:
- 描述瑞士大学儿童医院的药物处方模式.
- 调查处方模式与儿科住院患者的错误之间的关联.
主要方法:
- 对489名儿科患者和2693个处方的回顾性观察研究.
- 使用解剖治疗化学 (ATC) 系统分类的药物.
- 处方错误按类型 (PCNE) 和严重程度 (NCC MERP指数) 进行分析.
主要成果:
- 神经系统药物最常见 (42.6%),其次是食物药物 (15.6%) 和抗感染药物 (10.7%).
- 82%的患者接受了止痛药;最常见的是,甲米和布洛芬.
- 在2至11岁的儿童和女性患者中观察到潜在有害错误的更高率.
结论:
- 提供了关于一般医院病房儿科处方的见解.
- 突出了女性儿科患者处方错误的更高风险,需要进一步调查.
- 确定了具有反复错误的特定药物,建议针对性干预的领域.
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