动机增强干预措施以增加暴露前预防性预防性少数群体男性使用兴奋剂的使用:试验方案 序列式多重分配随机试验
Leah Davis-Ewart1, Christian Grov2, Rachel Verhagen3
1Health Promotion and Disease Prevention, Robert Stempel College of Public Health and Social Work, Florida International University, Miami, FL, United States.
JMIR research protocols
|October 13, 2023
概括
这项研究探讨了对使用兴奋剂以改善暴露前预防 (PrEP) 吸收的性少数群体男性的远程健康干预措施. 灵活,以参与者为中心的方法对于让这一群体参与艾滋病毒预防至关重要.
科学领域:
- 公共卫生 公共卫生
- 行为科学 行为科学
- 预防艾滋病毒 预防艾滋病毒
背景情况:
- 使用兴奋剂的性少数群体男性在获得暴露前预防 (PrEP) 服务方面面临挑战.
- 激励面试 (MI) 和应急管理 (CM) 显示出减少物质使用和无避孕套交 (CAS) 的希望,但需要适应PrEP参与.
- 现有的干预措施需要修改,以有效地支持PrEP护理在这个人群中持续坚持.
研究的目的:
- 测试远程医疗MI和CM组合的可行性,可接受性和初步有效性,以测试使用兴奋剂的 cisgender 性少数群体男性的 PrEP 准备.
- 评估通过远程医疗提供的动机增强干预措施的不同组合.
- 评估目前未使用PrEP的参与者对PrEP护理连续性的参与.
主要方法:
- 一项试点顺序多重分配随机试验 (PRISM) 涉及70名使用兴奋剂的 cisgender 性少数群体男性.
- 参与者通过社交网络应用程序在全国范围内招募,并完成了基线评估和邮寄HIV测试.
- 干预措施包括远程医疗MI和CM,为PrEP临床评估和处方履行提供财政激励,随后对未响应者进行第二次随机化.
主要成果:
- 招聘方面存在挑战,约有10%的符合条件的参与者报名参加.
- 在被录取者中,84%完成了邮寄的艾滋病毒检测,并确定了5个初步的艾滋病毒阳性结果.
- 该研究的实施突出了达到艾滋病毒预防优化目标人群的困难.
结论:
- 灵活,以参与者为中心的方法对于吸引使用兴奋剂的性少数群体男性参与艾滋病毒预防至关重要.
- 远程医疗平台可以扩大动机增强干预措施的覆盖范围和公共卫生影响,为这一优先级群体提供动力增强干预.
- 需要进一步的研究,以确定远程医疗MI和CM的有效性,以促进PrEP在这个人群中的使用.
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