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Updated: Jul 13, 2025

High-throughput Screening for Broad-spectrum Chemical Inhibitors of RNA Viruses
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High-throughput Screening for Broad-spectrum Chemical Inhibitors of RNA Viruses

Published on: May 5, 2014

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2-thiouridine是一种广泛的抗病毒核酸类比剂,用于对抗正链RNA病毒

Kentaro Uemura1,2,3,4, Haruaki Nobori2, Akihiko Sato2,3,5

  • 1Laboratory of Biomolecular Science, Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo 060-0812, Japan.

Proceedings of the National Academy of Sciences of the United States of America
|October 13, 2023
PubMed
概括

2-thiouridine (s2U) 对抗SARS-CoV-2和登革热病毒等RNA病毒具有广泛的抗病毒活性. 这种化合物抑制病毒RNA合成,改善动物模型的生存率.

关键词:
这是一种依赖RNA的RNA聚合酶.这就是SARS-CoV-2病毒.这是一种抗病毒药物.登革热病毒感染者阳性链RNA病毒.

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