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使用斯尼芬棒测试对偏头痛患者的嗅觉功能的评估:一项临床研究

Merih Karbay Efendioğlu¹, Elif Kocasoy Orhan¹, Cömert Şen²

¹Istanbul University, Istanbul Faculty of Medicine, Department of Neurology, Istanbul, Turkey.

American journal of otolaryngology

|October 13, 2023

概括

偏头痛患者表现出嗅觉功能障碍,与健康个体相比,嗅觉值和歧视发生变化. 这些嗅觉的变化也与偏头痛患者的全音体存在有关.

科学领域:

神经学神经学
神经科学是一个神经科学.
感官科学感官科学

背景情况:

偏头痛是一种复杂的神经疾病,通常伴有感官敏感性.
嗅觉功能障碍在偏头痛患者中曾经有过事报告,但系统评估是有限的.

研究的目的:

为了研究和比较偏头痛患者和健康对照者之间的嗅觉功能.
评估偏头痛患者的气味值,歧视和识别能力.

主要方法:

一项横截面受控的临床研究,涉及101名偏头痛患者和60名健康志愿者.
使用Sniffin' Sticks测试电池对嗅觉参数进行定量评估.
包括18岁及以上的参与者,根据国际头痛疾病分类-3标准诊断出偏头痛.

主要成果:

与对照组相比,偏头痛患者的气味值显著提高 (中位数为8.3比4.5),气味辨别得分较低 (中位数为10.0比12.0), (p < 0.001和p = 0.032).
更高的教育水平与更好的气味歧视和识别相关.
没有全音症的个体比具有全音症的个体明显更好地区分和识别气味 (p = 0.037和p = 0.034).

结论:

嗅觉功能,包括气味值,歧视和识别,在偏头痛患者和健康人群之间存在显著差异.
偏头痛中的Allodynia与较差的嗅觉性能有关,这表明传感处理和偏头痛病理生理学之间的潜在联系.

关键词:

偏头痛是一种偏头痛.嗅觉歧视嗅觉歧视气味识别气味识别气味识别气味的门值是什么臭氧恐惧症 (osmophobia) 是一种恐惧症.嗅探棒的气味测试嗅探棒的气味测试

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