癌症相关的状静脉血栓症:诊断时的临床特征和短期结果
Adrián García-Villa1, Juan José Criado-Álvarez2, María Carnevali3
1Department of Internal Medicine, Hospital Virgen del Puerto. Paraje Valcorchero S/N, 10600 Plasencia, Spain.
Thrombosis research
|October 13, 2023
概括
近40%的癌症患者患有静脉血栓症 (SVT) 是无症状的. 短期结局显示,患有SVT的症状和无症状癌症患者之间没有显著差异.
科学领域:
- 在瘤学瘤学.
- 血管医学 血管医学
- 胃肠病学 胃肠病学
背景情况:
- 脊柱静脉血栓症 (SVT) 在癌症患者中越来越多地被认可.
- 与癌症相关的SVT的临床意义和管理存在挑战.
- 了解SVT在这个人群中的表现和结果至关重要.
研究的目的:
- 描述与癌症相关的状静脉血栓症 (SVT) 的临床表现.
- 为了评估短期结果,包括死亡率,出血和复发,在癌症患者与SVT.
- 为了比较诊断出SVT的症状和无症状患者之间的结果.
主要方法:
- 在2015-2020年期间,对203名被诊断患有SVT的癌症患者进行了回顾性观察性研究.
- 根据SVT诊断呈现,患者被分类为有症状或无症状.
- 主要结局包括整体和SVT相关的死亡率,出血率和30天内血栓复发.
主要成果:
- 这项研究包括203名患者,其中腹内瘤 (76%) 和转移性疾病 (68%) 主要存在.
- 39%的患者在SVT诊断时无症状,而61%的患者有症状.
- 症状和无症状组之间没有观察到30天结果的显著差异,尽管无症状患者的死亡率较低 (3%vs10%).
结论:
- 大约40%的癌症相关的SVT病例是无症状的.
- 在患有SVT的症状和无症状癌症患者之间,短期结局没有显著差异.
- 需要进一步的研究来确定这些患者的最佳长期管理和结果.
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