一种针对塞马福林5A的全人类单克隆抗体减轻了类风湿性关节炎的进展

Yang Qin1, Jiayi Jin2, Jiani Zhang2

  • 1Institute of Autoimmune Diseases, School of Basic Medical Sciences, Wenzhou Medical University, Wenzhou, China; Department of Anesthesia and Critical Care, the Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China.

概括

一种名为SYD12-12的新抗体有效向SEMA5A (Semaforin 5A),对抗类风湿性关节炎 (RA). 在临床前模型中,这种治疗减少了关节损伤,改善了免疫平衡,为RA患者提供了有前途的新治疗策略.

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