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一种新的混合规则模型,用于预测直接压缩的药物混合物的流动性

Magdalini Aroniada1, Gabriele Bano2, Yuliya Vueva1

  • 1GlaxoSmithKline (GSK), Park Road, Ware SG12 0DP, United Kingdom.

International journal of pharmaceutics
|October 13, 2023
PubMed
概括

这项研究引入了一项新的混合规则,用于预测制药配方的粉末混合流动性. 该模型通过从单个组件数据中估计流量特性,减少了昂贵的实验测试,有助于直接压缩制造.

关键词:
混合规则 混合规则制药制造业 制药制造业 制药制造业通过设计的质量 (QbD)

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