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LncRNA NKILA通过抑制NF-κB信号激活来抑制HBV复制

Xi Zhang1, Yuanyuan Li2, Chen Huan2

  • 1Department of Infectious Diseases, Center of Infectious Diseases and Pathogen Biology, Key Laboratory of Organ Regeneration and Transplantation of the Ministry of Education, The First Hospital of Jilin University, Changchun, 130012, China; Institute of Virology and AIDS Research, The First Hospital of Jilin University, Changchun, 130012, China; Department of Ophthalmology, The First Hospital of Jilin University, Changchun, 130012, China.

Virologica Sinica
|October 13, 2023
PubMed
概括

与NF-κB相互作用的长非编码RNA (NKILA) 通过抑制NF-κB通路来抑制乙型肝炎病毒 (HBV) 复制. 乙型肝炎病毒感染降低了NKILA水平,这表明NKILA是HBV的潜在治疗点.

关键词:
慢性乙型肝炎病毒 (HBV)在此之前,HBx HBx这是一个LncRNARNA.在 NF-B 信号系统.与NF-κB相互作用的长非编码RNA (NKILA)病毒复制是病毒的复制.

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