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使用大型数据库,第三级AV阻塞和糖尿病之间存在强烈的独立关联
Mohammad Reza Movahed1, Ashkan Bahrami2, Coraly Manrique2
1University of Arizona College of Medicine, Tucson, AZ, United States; University of Arizona, College of Medicine, Phoenix, AZ, United States.
Diabetes research and clinical practice
|October 13, 2023
概括
糖尿病 (DM) 独立地与第三级心房 (AV) 阻塞有关. 这种联系持续了十多年,表明糖尿病和心律障碍之间存在重要联系.
科学领域:
- 心脏病学 心脏病学
- 内分泌学 在内分泌学.
- 公共卫生 公共卫生
背景情况:
- 新出现的数据表明,糖尿病类糖尿病 (DM) 和三度心室 (AV) 阻塞之间存在相关性.
- 这种关联的基本机制需要进一步阐明.
研究的目的:
- 调查DM与第三级AV阻塞之间的独立关联.
- 用一个大规模的国家住院病人数据库来分析这一关联.
主要方法:
- 使用了来自全国住院患者样本 (NIS) 数据库的DM和第三级AV阻塞的ICD-9代码.
- 分析了1992年和2002年的两个独立样本,代表了10年的间隔.
- 采用单变量和多变量分析来评估相关性,并根据相关的并发症进行调整.
主要成果:
- 在1992年,DM在第三级AV阻塞患者中的0.5%存在,而对照组的0.2% (OR:2.15).
- 2002年,DM患病率在第三级AV阻塞患者中为0.4%,对照组为0.2% (OR:1.86).
- 多变量分析在两年 (1992 OR: 2.54; 2002 OR: 1.56) 证实DM是第三级AV阻塞的独立风险因素,即使经过对年龄,CHF和CAD进行调整.
结论:
- 糖尿病独立地与第三级AV阻塞有关.
- 这种关联在10年内保持一致,突出显示了持久的联系.
- 需要进一步的研究来了解推动这种关系的因果关系.
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