当地点源空气污染中的不同挥发性有机化合物对与呼吸系统疾病相关的急诊室访问具有独特的高风险
Najm Alsadat Madani1, Laura E Jones2, David O Carpenter1
1Institute for Health and the Environment, University at Albany, Rensselaer, NY, 12144, USA; Department of Environmental Health Science, School of Public Health, University at Albany, Rensselaer, NY, 12144, USA.
Chemosphere
|October 13, 2023
概括
空气污染中的挥发性有机化合物 (VOC) 与喘和COPD等呼吸系统疾病的急诊室访问增加有关. 特定的挥发性有机化合物,如乙和,显示出显著的关联,突显了当地污染风险.
科学领域:
- 环境健康 环境健康
- 流行病学 流行病学
- 毒理学 毒理学 毒理学
背景情况:
- 空气污染,特别是颗粒物,是已知的呼吸道疾病的风险因素.
- 挥发性有机化合物 (VOC) 对呼吸系统的特定影响的研究是有限的.
- 了解VOCs的影响对于公共卫生和环境政策至关重要.
研究的目的:
- 调查邮政编码级挥发性有机化合物 (VOC) 污染与纽约州呼吸系统疾病的急诊室 (ER) 访问之间的联系.
- 确定有助于增加呼吸道疾病负担的特定VOC.
- 探索不同VOC之间的潜在相互作用效应.
主要方法:
- 使用的国家排放清单数据,用于2010-2018年邮政编码级VOC污染.
- 分析了四种呼吸道疾病的急诊室访问数据:喘,急性上呼吸道感染,COPD和下呼吸道疾病.
- 用于单一污染物模型的混合效应回归和多污染物模型的随机森林回归 (RFR),调整为社会经济因素.
主要成果:
- 在所有研究年中,在各种VOC和呼吸器ER访问之间发现了显著的关联,即使在调整贫困和吸烟之后.
- 乙基在喘,急性上呼吸道感染和COPD中显示出最重要的变量.
- 和是最重要的下呼吸道疾病,有证据表明双对VOC相互作用.
结论:
- 当地VOC污染显著增加了与呼吸系统疾病相关的急诊室访问的风险.
- 挥发性有机化合物的对呼吸系统健康的影响因特定化合物和疾病类型而异.
- 调查结果强调需要在公共卫生战略中考虑更广泛的空气污染物,包括VOC.
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