发生第二次发作的几率是多少?
Helen Saul1, Brendan Deeney1, Samantha Cassidy1
1NIHR Evidence, Twickenham, UK.
概括
在儿童中,第二次未引起的发作的可能性比成人更高. 这一发现影响了第一次发作的人的预后和治疗决策.
科学领域:
- 神经学 神经学
- 临床医学 临床医学
- 证据综合 证据综合
背景情况:
- 第一次无缘无故的发作需要准确的预后来指导管理.
- 了解复发风险对于患者咨询和治疗启动至关重要.
研究的目的:
- 系统地审查和综合有关儿童和成人第一次无缘性发作后预后的证据.
- 确定发作复发的风险,并确定影响预后的因素.
主要方法:
- 对相关研究进行了全面的系统审查和元分析.
- 提取和分析了关于发作复发,缓解和预后因素的数据.
主要成果:
- 在第一次未引起的发作后,儿童的复发风险明显高于成年人.
- 特定的临床和EEG发现会影响两年龄组复发的概率.
结论:
- 在儿童和成年人之间,第一个未引起的发作后的预后不同,需要针对年龄特定的治疗策略.
- 这些证据支持了关于进一步研究和治疗的知情决策.
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