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Updated: Jul 13, 2025

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高频脊髓刺激 (10 kHz) 在疼痛性糖尿病神经病变中改变感官功能和神经纤维密度:一项试点前性开放标签研究

Jeffrey Chen1, Katie Frizzi2, Shawn Zardouz1

  • 1Department of Anesthesiology, Center for Pain Medicine, University of California San Diego, La Jolla, CA, United States.

Pain medicine (Malden, Mass.)
|October 13, 2023
PubMed
概括

高频脊髓刺激 (10kHz SCS) 在患有疼痛性糖尿病神经病变的患者中有效缓解疼痛并改善神经功能. 这种治疗也导致神经纤维密度的可测量增加.

关键词:
10kHz的脊髓刺激频率为10kHz.神经纤维密度 神经纤维密度疼痛的糖尿病外围神经病变

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Local anesthetics (LAs) block the sodium channels of nerve trunks, sensory nerve endings, and neuromuscular junctions. Although LAs can block all kinds of nerves, the sensitivity of nerve fibers differs according to nerve types and structures. LAs are known to block myelinated fibers faster than unmyelinated ones. Also, they block pain or sensory neurons at low concentrations without affecting the motor neurons involved in muscle contractions. This helps relieve labor pain without affecting the...
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