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Updated: Jul 13, 2025

Characterize Disease-related Mutants of RAF Family Kinases by Using a Set of Practical and Feasible Methods
07:49

Characterize Disease-related Mutants of RAF Family Kinases by Using a Set of Practical and Feasible Methods

Published on: July 17, 2019

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对致癌性KRas4BG12V和Rgl2,一个RalA/B激活剂复合物的结构洞察

Mishal Tariq1, Teppei Ikeya2, Naoyuki Togashi2

  • 1Department of Molecular and Cell Biology, University of Leicester, Leicester, UK.

Life science alliance
|October 13, 2023
PubMed
概括

在人类癌症中,Ras异型的突变很常见. 这项研究揭示了瘤性Kras4B如何与RalGEFs相互作用,为癌症信号通路提供了洞察力.

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Utilizing 18F-FDG PET/CT Imaging and Quantitative Histology to Measure Dynamic Changes in the Glucose Metabolism in Mouse Models of Lung Cancer

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