在成年男性中,喉喉逆流和阻塞性睡眠呼吸暂停之间的关系
Lianlian Liu1, Xiaoyu Wang2, Jinhong Zhang2
1The Second School of Clinical Medicine, Southern Medical University, Guangzhou, Guangdong, China; Department of Otolaryngology-Head and Neck Surgery, The Sixth Medical Center of PLA General Hospital, Beijing, China.
Journal of voice : official journal of the Voice Foundation
|October 13, 2023
概括
阻塞性睡眠呼吸暂停 (OSA) 显著增加了喉回流 (LPR) 的风险. 患有OSA的患者会更频繁地出现LPR发作,这凸显了需要同时治疗这两种疾病的必要性.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 睡眠医学 睡眠医学
- 胃肠病学 胃肠病学
背景情况:
- 喉回流 (LPR) 是一种胃酸上升到喉的情况.
- 阻塞性睡眠呼吸暂停 (obstructive sleep apnea,简称OSA) 是一种睡眠障碍,其特征是不断阻塞呼吸道.
研究的目的:
- 调查阻塞性睡眠呼吸暂停 (OSA) 和喉回流 (LPR) 之间的关系.
- 为了确定OSA是否是LPR发展和症状严重性的风险因素.
主要方法:
- 一项涉及被诊断患有OSA的患者和没有OSA的对照组的比较研究.
- 使用反流症状指数 (RSI),反流发现信号 (RFS) 和24小时多通道内阻抗-pH (MII-pH) 监测进行评估.
- 在OSA和非OSA患者组之间比较LPR患病率和特征.
主要成果:
- 与对照组相比,OSA患者的LPR阳性率 (97.96%与75.68%) 和中位数LPR发作 (9与5) 显著更高.
- 阻塞性睡眠呼吸暂停 (OSA) 被确定为LPR (OR=9.995) 的重要危险因素.
- 在呼吸暂停-呼吸暂停指数和非酸性和性LPR发作之间发现了相关性.
结论:
- 阻塞性睡眠呼吸暂停 (OSA) 是喉回流 (LPR) 的已确认危险因素.
- 在患有OSA的个体中,LPR发作更频繁.
- 当OSA和LPR并存时,应考虑同时发生性LPR,包括胆汁反流.
相关概念视频
Sleep Apnea
164
Sleep apnea is a condition where breathing stops intermittently during sleep, often leading to significant health issues. Each episode can last from 10 to 20 seconds or more and is frequently accompanied by a brief arousal from sleep. This disturbance, largely unnoticed by the individual, can lead to severe daytime fatigue. Commonly, individuals seek help after being informed by their partners about loud snoring and noticeable breathing pauses during sleep.
The condition is more prevalent among...
The condition is more prevalent among...
164
Other Pulmonary Disorders
854
Respiratory disorders encompass a range of conditions with varying levels of severity. Asthma, marked by chronic airway inflammation and hypersensitivity, is one such condition. It can lead to airway obstruction due to factors like bronchial spasms, mucosal edema, increased mucus secretion, or epithelial damage. Asthma triggers are diverse, ranging from allergens to emotional upset, and treatment focuses on both immediate relief through bronchodilators and long-term inflammation suppression.
854
Gastroesophageal Reflux Disease II: Clinical Features and Management
105
Gastroesophageal reflux disease, or GERD, is a persistent medical condition that affects many individuals worldwide. Its clinical manifestations can vary greatly, making diagnosis and management challenging for healthcare professionals. The following is a comprehensive overview of the clinical manifestations, assessment, and management strategies for GERD.
Clinical Manifestations
GERD presents itself in a multitude of ways, with symptoms varying from person to person. The hallmark symptoms are...
Clinical Manifestations
GERD presents itself in a multitude of ways, with symptoms varying from person to person. The hallmark symptoms are...
105
Factors Affecting Pulmonary Ventilation
1.4K
Besides the pressure difference between the external environment and the lungs, the airflow rate and ease of pulmonary ventilation are also influenced by three other factors: surface tension of the fluid in the alveoli, compliance of the lungs, and airway resistance.
Alveolar Surface Tension
The alveolar fluid lines the luminal surface of the alveoli and exerts a force called surface tension. This force is caused by the polar water molecules in the liquid being more strongly attracted to each...
Alveolar Surface Tension
The alveolar fluid lines the luminal surface of the alveoli and exerts a force called surface tension. This force is caused by the polar water molecules in the liquid being more strongly attracted to each...
1.4K
Larynx
1.6K
The human larynx, often referred to as the voice box, is an intricate organ located in the neck. It serves as a pathway for air to enter the lungs during respiration and is an essential component of voice production.
Anatomy of the Larynx
The larynx consists of various components, including cartilage, muscles, and vocal cords. Its structure includes three large unpaired cartilages—the thyroid, cricoid, and epiglottis—and three smaller paired cartilages—the arytenoids,...
Anatomy of the Larynx
The larynx consists of various components, including cartilage, muscles, and vocal cords. Its structure includes three large unpaired cartilages—the thyroid, cricoid, and epiglottis—and three smaller paired cartilages—the arytenoids,...
1.6K
Anatomy of Respiratory System I: Upper Respiratory Tract
1.7K
The upper respiratory tract plays a vital role in the respiratory system, comprising several structures that facilitate air intake and prepare air for the lungs. It also serves as the first line of defense against pathogens and particles. This tract includes the nose and nasal cavity, the oral cavity, the paranasal sinuses, and the pharynx, each with specific functions and features.
Nose and nasal cavity
The nose and nasal cavity represent the main external openings of the respiratory tract....
Nose and nasal cavity
The nose and nasal cavity represent the main external openings of the respiratory tract....
1.7K


