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在大肠杆菌中基于Cas9的基因组工程的AcrIIC1抗CRISPR蛋白质的表征

Despoina Trasanidou1, Ana Potocnik1, Patrick Barendse1

  • 1Laboratory of Microbiology, Wageningen University and Research, Wageningen, The Netherlands.

Communications biology
|October 13, 2023
PubMed
概括

抗CRISPR蛋白质 (Acrs) 抑制了CRISPR-Cas9的活性. 研究人员使用AcrIIC1和热友Cas9变种开发了新的Acr基编辑工具,用于细菌中的基因编辑.

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