夜间喘发作是否会影响睡眠参数和炎症标志物? 一个基于人口的横截面研究
Maingredy Rodrigues Souza1, Daniela Santoro Rosa2, Tathiana A Alvarenga1
1Sleep Institute, São Paulo, Brazil.
Sleep & breathing = Schlaf & Atmung
|October 13, 2023
概括
夜间喘的严重程度与睡眠质量降低和阻塞性睡眠呼吸暂停 (OSA) 的风险增加有关. 持续性喘表明BMI较高,肺功能较差,OSA更频繁,但没有改变炎症标志物.
科学领域:
- 肺部病理学 肺部病理学
- 睡眠医学 睡眠医学
- 流行病学 流行病学
背景情况:
- 夜间喘症状可以显著影响睡眠质量和白天功能.
- 喘严重程度,睡眠障碍和炎症标志物之间的关系需要进一步调查.
研究的目的:
- 评估夜间喘严重程度对睡眠参数和炎症标志物的影响.
- 探索夜间喘和阻塞性睡眠呼吸暂停 (OSA) 之间的联系.
主要方法:
- 利用了来自圣保罗流行病学睡眠研究 (EPISONO) 版本 (2007年,2018年) 的数据.
- 通过验证的问卷,夜间多睡眠学,螺旋测量和血液样本分析炎症标志物收集数据.
- 根据间歇性或持续性夜间喘症状 (轻度,中度,严重) 分类参与者.
主要成果:
- 与那些有间歇性症状的人相比,持久性夜间喘的参与者表现出更高的BMI,更多的呼吸系统症状,更差的肺功能,以及较高的呼吸暂停-呼吸暂停指数 (AHI) 和脱指数.
- 在夜间喘和OSA之间发现了显著的关联,在持久性喘病例中OSA的患病率更高.
- 间歇性和持续性夜间喘组之间没有观察到免疫学参数的显著差异.
结论:
- 夜间喘症状是整体喘严重程度的关键指标.
- 这项研究加强了夜间喘和OSA之间的联系,强调了在喘管理中评估睡眠的重要性.
更多相关视频
05:31Noninvasive Sampling of Mucosal Lining Fluid for the Quantification of In Vivo Upper Airway Immune-mediator Levels
Published on: August 7, 2017
10.4K
04:53Author Spotlight: Traditional Chinese Medicine for Sleep Disorders in Acute COPD — A Safe, Cost-Effective Approach
Published on: October 18, 2024
819
相关概念视频
Asthma-III: Symptoms and Complications
2.5K
Asthma, a common chronic respiratory condition, is classified considering the frequency and severity of symptoms alongside lung function impairment. Understanding this classification is essential for appropriate treatment and management. Here's a detailed look at the classification of asthma and its clinical features and complications:
Classification of Asthma
Classification of Asthma
2.5K
Chronopharmacokinetics: Circadian Rhythms and Influence on Drug Response
69
Circadian rhythms are cyclic changes that are crucial in plasma drug concentrations. Various standard circadian parameters, including core body temperature, heart rate, and other cardiovascular factors, directly impact disease states and the therapeutic response to drug therapy.
The time of drug administration is an important factor to consider, as it can influence the toxic dose of a drug. For example, a study conducted by Prins et al. in 1997 examined the effects of the timing of...
The time of drug administration is an important factor to consider, as it can influence the toxic dose of a drug. For example, a study conducted by Prins et al. in 1997 examined the effects of the timing of...
69
Asthma: Pathogenesis and Management
421
Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
421
Asthma-II: Pathophysiology and Classification
2.7K
Asthma is a prevalent chronic respiratory condition marked by inflammation and hyperresponsiveness of the airways. Its pathophysiology involves complex interactions among inflammatory pathways, immune responses, and neural mechanisms.
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
2.7K
Asthma-I: Introduction
2.6K
Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...
2.6K
Asthma-IV: Diagnostic and Management
2.5K
The diagnosis and management of asthma are comprehensive, encompassing clinical assessments, lung function tests, and pharmacological interventions. Here's an overview:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
2.5K
