消毒剂对人类母乳中的骨质素度的影响
Kathleen G McClanahan1, Jeff Reese2, Jörn-Hendrik Weitkamp2
1Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN, USA.
Pediatric research
|October 13, 2023
概括
常见的母乳加工方法,如持有人巴氏杀菌和冷,显著降低了婴儿发育的重要蛋白质骨质蛋白. 这些技术降低了骨质疏松素水平,影响了其营养和发育益处.
科学领域:
- 生物化学 生物化学
- 人类牛奶科学 人类牛奶科学
- 婴儿营养 婴儿营养
背景情况:
- 骨质疏松素 (OPN) 是婴儿肠道,免疫和大脑发育必不可少的关键母乳蛋白质.
- 常见的牛奶加工和储存方法对OPN度的影响尚不清楚.
研究的目的:
- 为了研究标准母乳消毒和储存技术如何影响骨质素度.
- 为了量化由于持有人巴氏杀菌,回巴氏杀菌和冷而导致的骨质质素损失.
主要方法:
- 使用ELISA测量了新鲜,冷,持有人巴氏消毒和回巴氏消毒的人类母乳样本中的骨质素度.
- 在经过各种巴氏杀菌和冷协议后,分析了单一供体样本.
主要成果:
- 持有者巴氏杀菌导致骨质素度大约下降50%.
- 与持有人巴氏杀菌相比,回形巴氏杀菌导致OPN水平较低.
- 在持有人巴氏杀菌前冷母乳导致的OPN降解比冷前的巴氏杀菌要少.
结论:
- 常见的母乳加工方法,包括冷和持有人巴氏杀菌,显著降低生物活性骨质丁水平.
- 持有人巴氏杀菌平均减少了63%的OPN,而冷则导致了8-12%的减少.
- 结合巴氏杀菌和冷技术导致骨质疏松素损失较大.
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