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Updated: Jul 13, 2025

Hi-C: A Method to Study the Three-dimensional Architecture of Genomes.
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Published on: May 6, 2010

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从使用DARIC的Hi-C数据中识别定量差异化的染色体细分变化及其生物学意义

Yan Kai1, Nan Liu2,3, Stuart H Orkin4,5

  • 1Cancer and Blood Disorders Center, Boston Children's Hospital and Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, 02115, USA.

BMC genomics
|October 13, 2023
PubMed
概括

我们开发了DARIC,这是一个计算框架,用于量化染色体分离的变化. DARIC揭示了影响基因调节的大量变化,并提供了对基因组组织的新见解.

关键词:
三维基因组是3D的分区分的部分.分区化 分区化.基因调节 基因调节这就是Hi-C.核定位是指核定位.

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