认知功能和虚弱的动态,关联和时间序列:在中国社区居住的老年人中进行的一项纵向研究
Kai Cui1, Weihan Meng1, Zhiqiang Li1
1School of Public Health, Jinzhou Medical University, 40 Songpo Road, Jinzhou, 121000, P. R. China.
BMC geriatrics
|October 13, 2023
概括
在中国老年人中,认知功能和虚弱的关系是相互的,而不是单向的. 较高的初始认知能力与随着时间的推移较低的脆弱性有关.
科学领域:
- 老年学是一门学科.
- 神经科学是一个神经科学.
- 公共卫生 公共卫生
背景情况:
- 对中国老年人认知功能与虚弱之间纵向关联的理解有限.
- 在认知衰退和虚弱之间的关系中不明确的时间序列.
- 需要研究认知功能的方向性和脆弱动态.
研究的目的:
- 调查中国老年人认知功能和虚弱之间的纵向动态.
- 评估认知与脆弱之间关系的时间序列和方向性.
- 检查特定认知领域与脆弱性之间的关系.
主要方法:
- 利用了2824名中国老年人的数据,利用了潜增长和多变量潜增长模型.
- 采用交叉差距小组分析来确定虚弱和认知之间的时间关系.
- 分析了个体认知领域与脆弱状态之间的关联.
主要成果:
- 在认知功能和虚弱之间发现了显著的负面关联.
- 较高的基线认知功能预测了较低的初始脆弱性和较慢的脆弱性进展率.
- 观察到虚弱和认知功能之间存在相互关联,而不是单向的因果关系.
- 特定的认知领域显示了与基线和脆弱性变化率的不同负面关联.
结论:
- 在中国老年人中,认知功能和虚弱之间的关系是相互的.
- 随着时间的推移,认知表现和脆弱性相互影响.
- 不同的认知领域与脆弱有着不同的关联,凸显了它们相互作用的复杂性.
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