怀孕第一季度的苏丹妇女缺铁和甲状腺功能障碍:一个横截面研究
Wisal Abbas1, Abdelmageed Elmugabil2, Hamdan Z Hamdan3,4
1Faculty of Medicine, Kordofan University, Elobeid, Sudan.
BMC endocrine disorders
|October 13, 2023
概括
铁缺乏症 (ID) 在怀孕早期很常见,并且与甲状腺问题有关. 评估ID可以帮助预防孕妇甲状腺功能障碍.
科学领域:
- 内分泌学 在内分泌学.
- 孕产妇健康 孕产妇健康
- 营养科学 营养科学
背景情况:
- 孕妇面临铁缺乏症 (ID) 的敏感性增加,对母亲和产周健康构成风险.
- 现有的关于ID对甲状腺功能影响的研究缺乏来自撒哈拉以南非洲,特别是苏丹的数据.
- 这项研究通过检查苏丹孕妇的ID和甲状腺功能来解决这一差距.
研究的目的:
- 调查在怀孕第一季度期间苏丹妇女缺铁 (ID) 和甲状腺功能标志物之间的关联.
- 确定该人群中ID的患病率及其与甲状腺刺激激素 (TSH),自由三甲状腺素 (FT3) 和自由甲状腺素 (FT4) 的相关性.
主要方法:
- 在苏丹,对127名孕妇进行了横截面研究.
- 收集的数据包括产科/社会人口学特征,血红蛋白,血清费里丁,TSH,FT3和FT4水平.
- 统计分析包括t测试,曼-惠特尼U测试和斯皮尔曼相关性.
主要成果:
- 铁缺乏症 (ID) 很普遍,影响了127名登记的孕妇中的37%.
- 与没有ID的女性相比,ID的女性表现出明显较低的自由甲状腺素 (FT4) 水平.
- 血清费里与FT3呈现逆相关性,但与TSH或FT4.4没有发现显著相关性.
结论:
- 铁缺乏在怀孕的第一季度很常见,并与甲状腺功能障碍有关.
- 查和解决缺铁问题对于预防孕妇甲状腺功能障碍至关重要.
- 调查结果强调了对撒哈拉以南非洲地区有针对性的干预措施的必要性.
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