MGS2AMR:一种以基因为中心的挖掘病原体和其抗菌素耐药性概况的元基因组测序数据
Pieter-Jan Van Camp1, V B Surya Prasath1,2, David B Haslam2,3
1Division of Biomedical Informatics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 45229, USA.
Microbiome
|October 14, 2023
概括
一个新的管道,甲基因组测序到抗菌素耐药性 (MGS2AMR),分析甲基因组数据以检测抗生素耐药性基因 (ARG) 和它们在临床样本中的起源,为传统方法提供更快的替代方案.
科学领域:
- * 微生物学和基因组学
- * 生物信息学和计算生物学
背景情况:
- *从临床样本中识别传统的抗菌素耐药性 (AMR) 是耗时的,依赖于体外培养和敏感性测试.
- * 针对全基因组测序 (WGS) 数据的机器学习已经出现用于抗菌耐药性评估,但将其应用于元基因组数据仍然具有挑战性.
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